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WW DOMAINS
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DeCS
Descriptor
English
:
WW Domains
Descriptor
Spanish
:
Dominios WW
Descriptor
Portuguese
:
Domínios WW
Synonyms
English
:
Domain, WW
Domains, WW
WW Domain
Tree Number:
G02.111.570.820.709.275.750.500.937
Definition
English
:
An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins
and may be repeated up to four times in some
proteins
. It is characterized by two TRYPTOHAN residues (WW) about 20
amino acids
apart and folds into a stable triple-stranded BETA-SHEET. It binds
PROLINE-RICH PROTEIN DOMAINS
and
PHOSPHOSERINE
or PHOSPHOTHREONINE-containing
protein domains
that occur in many signal transducing and
cytoskeletal proteins
, such as
DYSTROPHIN.
History Note
English
:
2018
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
57257
Unique Identifier:
D000074585
Occurrence in VHL
:
Similar:
DeCS